This is more of the story of cell culture contamination and striking indifference in the scientific community. This post follows on from: http://asterisk.dynevor.org/how-much-do-scientists.html

If you’ve read that post, you will know that Walter Nelson-Rees did a lot of work in the 1970's to show that cell culture contamination was widespread. He left science in the early 1980's, shocked at the apparent hostility and indifference of the scientific establishment. Here is a quote about Nelson-Rees recorded on p145 of the book "A conspiracy of cells" by Michael Gold (1986).

"Nelson-Rees may have been exactly the right person for that time," explained one bureaucrat. "A more subtle and conciliatory style might not have spread knowledge of the extent of HeLa contamination throughout the world back then. Today, however, I would hope that there is sufficient awareness and sufficient expertise that any of these potential things would be avoided or caught quickly.

In fact cell-culture contamination rates appear to be about the same level then as now, at about 20%, and only 19% of published papers report cell-line authentication [1]

[1] Leonard P. Freedman et al (2015) "Reproducibility: changing the policies and culture of cell line authentication" Nature Methods 12(6) 493-7.

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