The editors of PLoS responding as editors to the article "Why most published research findings are false". 

"Too often editors and reviewers reward only the cleanest results and the most straightforward conclusions. At PLoS Medicine, we seek to create a publication environment that is comfortable with uncertainty. We encourage authors to discuss biases, study limitations, and potential confounding factors. We acknowledge that most studies published should be viewed as hypothesis-generating, rather than conclusive. "

From: http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.0020272

The direction the PLoS editors are going comes from the beginning quote in this article:

"Truth in science can be defined as the working hypothesis best suited to open the way to the next better one.”—Konrad Lorenz, Austria

This just shifts the blame from the editors to the readers.  False findings generate false hypotheses.

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