Are preclinical drug studies becoming less replicable at a rapid rate?
"Phase II [clinical drug trial] success rates for new development projects have fallen from 28% (2006–2007) to 18% (2008–2009)"
The most common reported cause for failure is lack of efficacy of the drug.
http://www.nature.com/nrd/journal/v10/n5/full/nrd3439.html
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